Over 58 million Americans have actinic keratosis, a skin condition caused by damage from the sun’s ultraviolet (UV) rays. With this condition, you develop scaly, discolored spots called actinic ... The New England Journal of Medicine: Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis The tubulin polymerization and Src kinase signaling inhibitor tirbanibulin is being investigated as a topical treatment for actinic keratosis, a precursor of squamous-cell carcinoma.

Understanding the Context

In two ... An actinic keratosis is a very common and treatable precancerous skin lesion. Our dermatologist Saira George, M.D., explains what causes actinic keratoses, how to treat them and who’s at risk. Actinic keratosis (pronounced ak-TIN-ik ker-uh-TOH-sis), also known as solar keratosis, is a skin condition that happens with too much sun exposure.

Key Insights

It causes rough, scaly spots of skin. Also known as a solar keratosis, an actinic keratosis grows slowly and usually first appears in people over 40. You can reduce your risk of this skin condition by minimizing your sun exposure and protecting your skin from ultraviolet (UV) rays. View images and learn the warning signs and symptoms for the precancer actinic keratosis (AK) and how to spot it early. What is an actinic keratosis?

Final Thoughts

Actinic keratosis is a precancerous scaly spot found on sun-damaged skin, also known as solar keratosis. It may be considered an early form of cutaneous squamous cell carcinoma (a keratinocyte cancer).