A scoring system has been developed to help distinguish between two diseases. Left: generalized pustular psoriasis (GPP). Right: acute generalized exanthematous pustulosis (AGEP).

Understanding the Context

Your skin becomes ... Acute generalised exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction and is attributed to drugs in more than 90% of cases. It is a rare disease, with an estimated incidence of 1–5 patients per million per year. EurekAlert!: Keeping score: novel method might help differentiate 2 serious skin diseases Acute Generalised Exanthematous Pustulosis (AGEP) is a rare, severe cutaneous adverse reaction that most frequently occurs in response to medications.

Key Insights

It is characterised by a rapid onset of ... News Medical: Novel scoring system can distinguish between two serious skin diseases Acute generalised exanthematous pustulosis (AGEP) is an uncommon pustular drug eruption characterised by superficial pustules. Over 90% of cases of AGEP are provoked by medications. Acute generalized exanthematous pustulosis (AGEP) is a rare, acute, severe cutaneous adverse reaction characterized by the development of numerous nonfollicular, sterile pustules on a background of edematous erythema [1-3]. Acute generalized exanthematous pustulosis (AGEP; also known as pustular drug eruption and toxic pustuloderma) is a rare skin reaction that in 90% of cases is related to medication.

Final Thoughts

AGEP is characterized by sudden skin eruptions that appear on average five days after a medication is started.