chilblain lupus - Health Topics
Chilblain lupus is a rare complication of cutaneous lupus erythematosus (lupus that affects your skin). The condition causes painful red or purplish sores, usually on your fingers or feet. Chilblain lupus erythematosus (CHLE) is a rare type of cutaneous lupus erythematosus.
Understanding the Context
Learn about the symptoms, causes, treatments, and more. Chilblain lupus is caused by genetic mutations, also known as pathogenic variants. Genetic mutations can be hereditary, when parents pass them down to their children, or they may occur randomly when cells are dividing. Chilblain lupus | About the Disease | GARD - Genetic and Rare Diseases ...
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Key Insights
Chilblain Lupus is a rare condition with causes linked to cold exposure. Learn about its symptoms, diagnosis methods and effective treatments Wonder if purple toes mean more than cold exposure? Learn the tell-tale signs, tests, and treatments that separate chilblain lupus from “regular” chilblains. Chilblain lupus erythematosus is characterized by a rash that primarily affects acral surfaces that are frequently exposed to cold temperatures, such as the toes, fingers, ears, and nose. Chilblain lupus is a rare type of chronic cutaneous lupus erythematosus (CLE).
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It is characterized by red or violaceous papules and plaques located on acral areas (Figure 1). Chilblain lupus causes painful skin lesions from inflamed blood vessels. Learn symptoms, causes, and treatments to manage this chronic autoimmune condition. Chilblain lupus erythematosus is a rare, cold-induced form of chronic cutaneous lupus that can occur in both genetic and sporadic forms. It is characterized by acral skin lesions and is commonly associated with autoimmunity and type I interferon pathway activation. Chilblain lupus: A rare form of cutaneous lupus erythematosus — A case ...