Patients with culture-negative infective endocarditis differ in presentation and features of the disease from those with culture-positive infective endocarditis but have similar survival outcomes. The New England Journal of Medicine: Bacterial Endocarditis Following Surgery for Congenital Heart Disease BEFORE the antibiotic era subacute bacterial endocarditis was almost invariably a fatal complication in congenital and acquired heart disease. 1–3 The offending organism was Streptococcus viridans in ...

Understanding the Context

Endocarditis is a life-threatening disease that involves inflammation of the endocardium, heart valve, and vascular intima. Endocarditis is caused by pathogenic bacteria - around 90% of the cases are ... Healio: Valve replacement resulting in endocarditis may occur in congenital heart disease Open Heart: Long-term outcomes of mitral valve surgery in infective endocarditis: a single-centre UK experience Background The optimal surgical strategy for mitral valve (MV) infective endocarditis (IE) remains uncertain. Although valve repair is increasingly advocated, MV replacement is frequently performed, ...

Key Insights

Long-term outcomes of mitral valve surgery in infective endocarditis: a single-centre UK experience