Graft-versus-host disease (GVHD) following liver transplantation remains a rare but devastating complication, characterised by donor immunocompetent cells initiating an immune attack against host ... Patients receiving post-transplant cyclophosphamide to prevent graft-versus-host disease have lower risk for bronchiolitis obliterans syndrome. News Medical: New assessment framework improves evaluation of cutaneous chronic graft-versus-host disease Benzinga.com: Penny Stock Equillium Falls After Itolizumab Treatment Fails To Show Improvement In Response Rates In Graft Versus Host Disease Patients Penny Stock Equillium Falls After Itolizumab Treatment Fails To Show Improvement In Response Rates In Graft Versus Host Disease Patients ascopubs.org: Is It Time to Move Beyond Graft-Versus-Host Disease-Free, Relapse-Free Survival as a Primary End Point in Clinical Trials for Hematopoietic Cell Transplantation?

Understanding the Context

Is It Time to Move Beyond Graft-Versus-Host Disease-Free, Relapse-Free Survival as a Primary End Point in Clinical Trials for Hematopoietic Cell Transplantation? MarketWatch: Orca Bio Announces Orca-T(R) Phase 3 Data Published in Blood Demonstrate Significant Improvement in Survival Free from Chronic Graft versus Host Disease in Patients with ... Orca Bio Announces Orca-T(R) Phase 3 Data Published in Blood Demonstrate Significant Improvement in Survival Free from Chronic Graft versus Host Disease in Patients with ... People with severe symptoms of chronic graft versus host disease (GvHD) often need to use multiple treatments to manage their condition.

Key Insights

In recent years, a new class of medicines known as kinase ... News Medical: Oral fecal transplantation could help prevent graft-versus-host disease in stem cell transplant patients A new study shows that oral fecal microbiota transplantation (FMT) is a feasible and safe addition to preventing graft-versus-host disease in patients undergoing stem cell transplantation for blood ... Oral fecal transplantation could help prevent graft-versus-host disease in stem cell transplant patients It’s possible to manage graft-versus-host disease (GVHD) with appropriate treatments. Your individualized treatment plan will depend on your symptoms, their severity, and the disease’s response to ... Symptoms of graft-versus-host disease (GVHD), a complication of allogeneic hematopoietic stem cell transplant, can be mild to life threatening.

Final Thoughts

Symptoms may affect your skin, gastrointestinal tract, ... Healio: More research needed to better discern differences in graft-versus-host disease, dry eye More research needed to better discern differences in graft-versus-host disease, dry eye ascopubs.org: The metabolic profiles of patients with autologous hematopoietic stem cell transplantation with graft versus host disease. The metabolic profiles of patients with autologous hematopoietic stem cell transplantation with graft versus host disease. Medical News Today: What are the treatment options for graft-versus-host disease (GVHD)? Steroid therapy is the first-line treatment for graft-versus-host disease (GVHD). If GVHD does not respond to initial therapies, doctors may consider chemotherapy, monoclonal antibodies, and other ...

FiercePharma: Incyte, Syndax bag FDA approval for potential blockbuster Niktimvo in graft-versus-host disease Incyte has expanded its graft-versus-host disease (GVHD) offerings beyond Jakafi. The new addition comes from axatilimab, a CSF-1R inhibitor partnered with Syndax Pharmaceuticals. Wednesday, the drug ... Incyte, Syndax bag FDA approval for potential blockbuster Niktimvo in graft-versus-host disease When chronic graft-versus-host disease (GVHD) causes inflammation in your digestive system, symptoms like mouth sores, stomach pain, diarrhea, and food sensitivity can make it difficult to eat.