“Groove sign ”– a linear depression following the path of superficial veins in the affected area, best appreciated with elevation of the limb and tangential lighting. Groove sign is a classical and characteristic feature of EF and can be observed as a depression along superficial veins, best visualized when the limbs are elevated. The groove sign, or vertical linear depressions along superficial veins, is a characteristic finding of EF made prominent by limb elevation.

Understanding the Context

MRI is the ideal imaging modality for diagnosing EF, 2 and the skin-to-muscle biopsy is the gold standard of diagnosis. 3 The groove sign, a linear depression along the superficial veins, is a characteristic physical finding of EF, 4 and its presence helps to diagnose EF. The groove sign refers to the visible grooves or depressions that form on the affected areas of the skin when pressure is applied. This sign is helpful in distinguishing eosinophilic fasciitis from other similar conditions, aiding in accurate diagnosis and appropriate treatment.

Key Insights

A classical clinical finding of eosinophilic fasciitis is the ‘groove sign’ which is a linear depression along the course of veins, accentuated by limb elevation, due to inward tethering of the skin. Groove sign is a characteristic finding of eosinophilic fasciitis, consisting of a depression along the course of the superficial veins, more marked on elevation of the affected limb. Fig. 1 A and B: “the groove sign”; it has been hypoth-esized that the epidermis and superficial dermis around the vessels were less afected by the fibrotic process than the deep tissue.