The New England Journal of Medicine: Acute Disseminated Lupus Erythematosus Associated with Finger Lesions Resembling Lupus Pernio — Report of a Case Acute Disseminated Lupus Erythematosus Associated with Finger Lesions Resembling Lupus Pernio — Report of a Case Lupus pernio presents as bluish-red or violaceous nodules and plaques over the nose, cheeks and ears. The name is derived from the Latin name for 'wolf' (lupus) and for 'chilblain' (pernio). Lupus pernio is a cutaneous manifestation of sarcoidosis, which was first described in 1889 by Ernest Besnier.

Understanding the Context

It presents as a violaceous lesion or shiny nodules over the head and neck but is predominantly localized to the nose, cheeks, and ears. [1] Lupus pernio is a chronic raised indurated (hardened) lesion of the skin, often purplish in color. It is seen on the nose, ears, cheeks, lips, and forehead. Lupus pernio is a skin-related symptom of a disease called sarcoidosis, which was first identified by Ernest Besnier in 1889.

Key Insights

It appears as a purple-colored shiny bumps on the head and neck, but it’s mainly found on the nose, cheeks, and ears. Lupus pernio causes purplish, swollen skin lesions, often linked to sarcoidosis. Learn about its symptoms, causes, and treatment options for proper management. Lupus pernio refers to an indurated, violaceous, plaque-like eruption that most frequently occurs on the nose, cheeks, chin, and forehead. This manifestation tends to affect black women more commonly and is associated with upper respiratory disease, pulmonary fibrosis, and bony involvement.

Final Thoughts

Lupus pernio (LP) is a chronic non-life threatining type of cutaneous sarcoidosis that can be related to chronic fibrotic sarcoidosis, hyperglobulinemia and hypercalcemia. Lupus pernio is one of the most important clinical clues for this disease with higher risk for pulmonary disease.