Morphoea (American spelling, morphea) is characterised by an area of inflammation and fibrosis (thickening and hardening) of the skin due to increased collagen deposition. It is also known as localised scleroderma. The term 'scleroderma' covers various types of morphoea and systemic sclerosis.

Understanding the Context

Get an overview of morphea, including morphea symptoms, causes, treatment, risk factors for the disease, and potential complications. Learn more about types of morphea, including linear, profunda and localized morphea, more accurately known as localized scleroderma. The Janus kinase (JAK) inhibitor ruxolitinib (Jakafi) eased the severe inflammatory and dermatologic symptoms of disabling pansclerotic morphea (DPM), an initial clinical series showed. After a series ...

Key Insights

Morphea is a rare skin condition characterized by small red or purple patches that develop firm white or ivory centers. The affected skin becomes tight and less flexible. Morphea is a form of scleroderma that mainly involves isolated patches of hardened skin on the face, hands, and feet, or anywhere else on the body, usually with no internal organ involvement. [1] Morphea scleroderma, more commonly known as morphea, is a skin condition characterized by discolored and thickened patches of skin on various areas of the body. Morphea is a skin condition that involves a patch or patches of discolored or hardened skin on the face, neck, hands, torso, or feet.

Final Thoughts

The condition is rare and thought to affect less than 3 out... Morphea (syn. localized scleroderma) occurs as a result of autoimmune fibrosing (leather-like) injury to the skin and sometimes the underlying fat, muscle and bone.