Most people with lupus have it affect the skin. The types of rashes can be divided into two large groups. First, when lupus affects the skin with problems only seen in lupus, it’s called cutaneous ...

Understanding the Context

An oral therapy targeting toll-like receptors (TLR) 7 and 8 reduced disease activity in patients with cutaneous lupus erythematosus (CLE) or systemic lupus erythematosus (SLE) with active lupus rash. Different kinds of skin rashes include eczema, chickenpox, psoriasis, and shingles. Treatment depends on what's causing your rash, but it may involve medications or lifestyle changes. Get medical care ...

Rashes - Peak Dermatology

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Rashes - Peak Dermatology
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Key Insights

Lupus is a chronic (long-lasting) autoimmune disease. This webpage focuses on systemic lupus erythematosus (SLE), the most common form of lupus. Lupus is different for each person and can affect different areas of the body, including: skin; joints; heart; lungs; kidneys; and the brain. If you have lupus, you may have times of more symptoms (flares) and times of feeling better (remission). The Accelerating Medicines Partnership® Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP® RA/SLE) program launched in 2014 as one of the original components of the Accelerating Medicines Partnership (AMP).

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Final Thoughts

PGZ induces significant improvements in vascular stiffness and cardiometabolic parameters in SLE. The role of PGZ as a modulator of cardiovascular disease risk in SLE should be further explored. The unit's SLE Natural History and Pathogenesis protocol is crucial for understanding the disease's diversity, offering vital biological samples and clinical phenotyping for research. Our collaborative approach has resulted in significant biomarker discoveries and the development of new clinical trials. The findings suggest that NR is a potential adjunct to lupus treatment. What is exciting about this article?

A key part of SLE clinical management is decreasing proinflammatory and type I interferon (IFN) responses to prevent further tissue damage and critical cardiovascular events.