Stevens-Johnson syndrome is a mucocutaneous immune-mediated hypersensitivity reaction. It is often triggered by drugs or infections. It presents as a skin and mucous membrane drug hypersensitivity ...

Understanding the Context

SJS-TEN images. Images of Stevens Johnson syndrome / toxic epidermal necrolysis. Authoritative facts from DermNet New Zealand. What are Stevens–Johnson syndrome and toxic epidermal necrolysis?

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Key Insights

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are now believed to be variants of the same condition, distinct from erythema multiforme. SJS/TEN is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal ... Stevens-Johnson syndrome Fixed drug eruption Bullous pemphigoid Paraneoplastic pemphigus Polymorphous light eruption Rowell syndrome (erythema multiforme-like lesions in systemic lupus erythematosus) What is the treatment for erythema multiforme? Treatment is often not needed as episodes are typically self-limiting with no ongoing complications. Stevens–Johnson syndrome/toxic epidermal necrolysis Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a severe, life-threatening illness with blistering of the mouth and other mucous membranes and widespread macular rash, with detachment of the epidermis from the dermis.

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Final Thoughts

Triggers for Stevens Johnson syndrome / toxic epidermal necrolysis. Authoritative facts about the skin from DermNet New Zealand. What is Stevens Johnson syndrome / toxic epidermal necrolysis? Stevens Johnson syndrome /toxic epidermal necrolysis (SJS/TEN) is a very severe and acute skin disease, almost always caused by a drug. SJS/TEN is characterised by an extensive necrosis and detachment of the epidermis, which involves skin and mucosal surfaces (genitals, eyes, and mouth). The nursing care described on this page is ...

The skin conditions that may sometimes be difficult to distinguish from AGEP include: Stevens-Johnson syndrome / toxic epidermal necrolysis Drug hypersensitivity syndrome Other drug eruptions Generalised pustular psoriasis Neutrophilic dermatoses Acute localised exanthematous pustulosis. How is acute generalised exanthematous pustulosis treated? Toxic epidermal necrolysis (TEN) is a severe cutaneous drug reaction characterised by a prodromal 'flu-like illness followed by the rapid appearance of a painful erythematous rash and desquamation of skin and mucous membranes. TEN is at the severe end of a spectrum with Stevens-Johnson syndrome defined by >30% body surface area skin detachment.