The immunosuppressive agent tacrolimus, commonly used for solid organ transplantation, may have a therapeutic role in systemic lupus erythematosus (SLE), particularly for lupus nephritis, European ... The American Journal of Managed Care: Tacrolimus Linked to Lower Acute GVHD Risk Tacrolimus and cyclosporine A show similar efficacy in long-term survival and relapse reduction in AML post-transplant patients. No significant differences were found in leukemia-free survival, ...

Understanding the Context

Healio: Tacrolimus shows promise in treatment of dermatologic conditions with risk factors Please provide your email address to receive an email when new articles are posted on . Tacrolimus may be promising for patients with psoriasis or atopic dermatitis who also have cardiovascular risk ... To evaluate the efficacy and safety of topical 0.005% tacrolimus eye drop for treatment of refractory vernal keratoconjunctivitis (VKC). This prospective study included 20 eyes of 10 patients with ...

Key Insights

The 354 subjects were randomly divided into a development (60%) and a validation cohort (40%). The data from the development cohort (212 subjects with 3704 troughs) were used to build the apparent ... A trial supports the use of the calcineurin-inhibitor tacrolimus as a targeted treatment for uremic pruritus and introduces IL-13 inhibition as a viable mechanism to address cytokine-mediated itch.