Acrodermatitis enteropathica is a rare skin disorder associated with zinc deficiency. Congenital and acquired forms of the condition exist. Treatment, usually involving zinc supplements, can ...

Understanding the Context

Acrodermatitis, or Gianotti-Crosti syndrome, is a common skin condition that typically affects children between the ages of 3 months and 15 years. The full name of the disease is “papular... Papular acrodermatitis of childhood presents over the course of 3 or 4 days. A profuse eruption of dull red spots develops first on the thighs and buttocks, then on the outer aspects of the arms, and finally on the face.

Key Insights

Gianotti-Crosti syndrome (GCS), also known as papular acrodermatitis, papular acrodermatitis of childhood, and infantile papular acrodermatitis, is a self-limited skin disorder that most often occurs in young children. It is a diffuse chronic skin disease usually confined to the limbs, seen mainly in women in Northern, Central, and Eastern Europe, and characterized initially by an erythematous, oedematous, pruritic phase followed by sclerosis and atrophy. It is caused by infection with Borrelia burgdorferi. [3] Papular Acrodermatitis, also known as Gianotti-Crosti Syndrome, is a rare viral rash that primarily affects children and is characterized by small, raised bumps on the skin. Learn about the causes, symptoms, and treatment options for acrodermatitis, a skin condition affecting children and adults.

Final Thoughts

Acrodermatitis enteropathica (AE) is a disorder of zinc metabolism that can either be inherited or acquired. Both forms lead to the inability to absorb zinc from the intestine.