idiopathic thrombocytopenic purpura - Health Topics
ascopubs.org: Successful Treatment With Tacrolimus of a Patient With Severe Idiopathic Thrombocytopenic Purpura After Allogeneic Bone Marrow Transplantation Successful Treatment With Tacrolimus of a Patient With Severe Idiopathic Thrombocytopenic Purpura After Allogeneic Bone Marrow Transplantation Once known as idiopathic thrombocytopenic purpura, ITP can cause purple bruises. It also can cause tiny reddish-purple dots on the skin that look like a rash. Children can get ITP after a virus.
Understanding the Context
They most often get better without treatment. In adults, the illness often lasts months or years. Immune thrombocytopenia (ITP; also called idiopathic thrombocytopenic purpura, immune thrombocytopenic purpura) is an acquired thrombocytopenia caused by autoantibodies against platelet antigens. It is one of the more common causes of thrombocytopenia in otherwise asymptomatic adults.
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Key Insights
Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenia, is a rare bleeding condition or a platelet disorder in which the immune system unintentionally attacks and destroys blood platelets, resulting in severe bruising and bleeding. ITP is caused by an immune reaction against your own platelets. This means that your body’s immune system attacks your platelets by mistake. ITP is a rare autoimmune blood disorder that both children and adults can develop. There are 2 forms of ITP: Acute thrombocytopenic purpura.
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The term "idiopathic" no longer applies, because the etiology is known, and the term "purpura" has been abandoned because it is misleading: almost one-third of patients with newly diagnosed... The New England Journal of Medicine: Use of the Plasma Acid Phosphatase Value in the Differentiation of Thrombocytopenic States